0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Insulin Injections: Rotation of Anatomic Regions and Plasma Glucose-Reply

John P. Bantle, MD; R. Paul Robertson, MD
JAMA. 1990;264(12):1536. doi:10.1001/jama.1990.03450120047024.
Text Size: A A A
Published online

In Reply.—  Dr Bernstein suggests that when diabetic individuals are treated with a few large doses of insulin each day, blood glucose levels are more variable than when they are treated with more frequent injections of small doses of insulin. We share this impression. However, many diabetic patients are unwilling to inject insulin four or five times daily as suggested by Dr Bernstein. Moreover, when this issue was studied systematically, Service and coworkers1 found that individuals with unstable diabetes who were switched from one or two daily injections of intermediate-acting insulin to four daily injections of short-acting insulin did not demonstrate a reduction in the lability of blood glucose as measured by the mean amplitude of glycemic excursions. Regardless of whether patients with type I diabetes take one or two large doses or more frequent smaller doses of insulin each day, we believe that the day-to-day variability of blood glucose

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();