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Article |

Hematology: A Pathophysiological Approach

O'Neill Barrett Jr, MD
JAMA. 1990;264(6):758. doi:10.1001/jama.1990.03450060104044.
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This is the second edition of the hematology text by Babior and Stossel. It is a splendid book and differs from more traditional works on hematology in several ways.

The authors emphasize that their approach has been to emphasize pathophysiological mechanisms, and they do this very well. They also point out that to be effective, they have changed some of the traditional classification systems; this approach is interesting and, for the most part, successful. For example, autoimmune thrombocytopenia is classified under the section on "Immune Destruction of Blood Cells," which deals with not only platelets, but red and white blood cells as well. On the other hand, one cannot find a discussion of the general topic of thrombocytopenia, especially those conditions causing decreased platelet formation. Likewise, thrombocytosis is dismissed with a one-paragraph comment about the ineffectiveness of antiplatelet drugs in this condition.

In general, the book is well organized and


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