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Louis Lasagna, MD
JAMA. 1990;264(6):757-758. doi:10.1001/jama.1990.03450060103043.
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Pharmacoepidemiology is a growing discipline. Population studies of drug effects are of increasing importance to the pharmaceutical industry, the Food and Drug Administration, litigants, and the medical profession. Information about the adverse effects of drugs derives partly from controlled clinical trials performed prior to registration of a drug, but many effects of interest do not come to light until a drug is taken by large numbers of patients. Nailing down association between a drug and patient injury is difficult; proving causality is even harder.

Strom, one of the bright young American pharmacoepidemiologists, has convinced a number of the gurus in the field to write chapters for this book, which can easily serve as a primer for those wishing to get a start on their education in pharmacoepidemiology.

Almost half of the book is devoted to individual descriptions of various databases available for pharmacoepidemiologic studies, with attention to their advantages and


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