We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Efficacious Treatments of PMS: A Need for Further Research

Howard J. Osofsky, MD, PhD
JAMA. 1990;264(3):387. doi:10.1001/jama.1990.03450030111043.
Text Size: A A A
Published online


Many women of childbearing age have some premenstrual symptoms. In various reports, between 3% and 15% have severe symptoms. The symptoms of premenstrual syndrome (PMS) have been described in poignant detail by patients, their families, and physicians for thousands of years. However, empirical data about this elusive and somewhat confusing syndrome have been obtained primarily during this century, and especially during recent years. Frank1 and Horney2 separately in 1931 described versions of PMS, explored possible etiological bases for the symptoms, and suggested approaches to treatment. Since that time, interest and research related to the syndrome have waxed and waned. Perhaps in part related to difficulties in obtaining direct hormonal assays, the myriad symptoms associated with PMS, and methodological difficulties and flaws in design, considerable disagreement has persisted concerning whether there is a well-defined syndrome, whether it should be defined as an emotional or physical disorder, what the etiological


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.