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ARTICLE | July 18, 1990

Invasive Meningococcal Conjunctivitis

Fernando A. Moraga, MD; Pere Domingo, MD; Nicolau Barquet, MD; Isabel Gasser, MD; Alfredo Gallart, MD

JAMA. 1990;264(3):333-334. doi:10.1001/jama.1990.03450030049014.

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To the Editor.— Systemic meningococcal infections are presumed to follow spread of meningococci from the nasopharynx into the blood and then to the cerebrospinal fluid.¹ However, there have been reports of at least 10 cases of systemic meningococcal infection in which the conjunctiva was the probable portal of entry.^2-11 The overall incidence of invasive meningococcal conjunctivitis has been estimated to be about 10% of the cases of primary meningococcal conjunctivitis.¹²Neisseria meningitidis was isolated from conjunctival exudate in 21 patients with acute bacterial conjunctivitis who were treated at our hospital during the last 5 years. During this period, 1030 patients with a microbiologically proved acute bacterial conjunctivitis were diagnosed, which gives an incidence for N meningitidis conjunctivitis of 2.0%. Six (28.6%) of our 21 patients with primary meningococcal conjunctivitis, after a mean interval of 27.1 (±23.8) hours from the appearance of the initial ocular symptoms, developed systemic

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Moraga FA, Domingo P, Barquet N, Gasser I, Gallart A. Invasive Meningococcal Conjunctivitis. JAMA. 1990;264(3):333-334. doi:10.1001/jama.1990.03450030049014.

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