The Presence of Alzheimer's Disease in a Community Population

Lissy F. Jarvik, MD, PhD
JAMA. 1990;263(18):2448. doi:10.1001/jama.1990.03440180045022.
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To the Editor.—  The intriguing results reported from the study in East Boston by Evans et al1 raise a number of concerns regarding their public health implications.2 Some data already in the literature support the high prevalence rates, eg, in the first US prospective study of the development of dementia in community residents,3-5 the prevalence of dementia (all degrees, from mild to severe) was 48% (N = 52) for those aged 80 years and older.3 This result, obtained in New York State from a small group of surviving twins, who had been followed up for 25 years or more, is remarkably similar to that from the East Boston study,1 as well as those of the much older Scandinavian epidemiologic studies,6,7 in which dementia was reported for 47% (N = 55) and 48% (N = 175) of those aged 80 years or older.Dementia due to vascular conditions


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