We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Exercise, Fitness, and Mortality-Reply

Steven N. Blair, PED; Harold W. Kohl III, MSPH; Ralph S. Paffenbarger Jr, MD, DrPH
JAMA. 1990;263(15):2047-2048. doi:10.1001/jama.1990.03440150051015.
Text Size: A A A
Published online


In Reply.—  Dr Goldstein is correct in his suggestion that the inverse relation in our study between physical fitness and cancer mortality might be confounded by undiagnosed cancer present at baseline examination. Preclinical cancer could result in poor treadmill test performance and increase the likelihood of death due to cancer during follow-up. To address this issue, we excluded all cancer deaths that occurred in the cohort during the first 3 years of follow-up and reanalyzed the relation between fitness and cancer mortality. This exclusion left 55 cancer deaths in men and 13 in women. Age-adjusted cancer death rates per 10 000 person-years of observation in low-, moderate-, and high-fitness groups were 16.4, 6.1, and 4.5 in men and 13.5, 5.9, and 1.0 in women, respectively. These findings reduce the likelihood that preclinical cancer is the sole cause of the relation between fitness and cancer. However, residual confounding from prior cigarette


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.