We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Autologous Blood Donations Before Elective Cardiac Surgery-Reply

Debra V. Owings, MD; Margot S. Kruskall, MD; Robert L. Thurer, MD; Lillian M. Donovan
JAMA. 1990;263(9):1202. doi:10.1001/jama.1990.03440090032021.
Text Size: A A A
Published online


In Reply.—  We appreciate Dr Avoy's comments concerning our article and would like to respond to the two points he makes in the letter. First, a question is raised about the need to administer saline to donors concomitant with blood collection to forestall reactions. The pathophysiology of the "vasovagal reaction" during and following blood donation, even in normal donors, is poorly understood. The primary cause is probably neurological. However, the extent of the acute decrease in blood volume resulting from donation must also be important, since the reaction rate in donors of 200 mL of blood is lower (1.3%)1 than in donors of 400 to 500 mL (3.7% to 6.0%).2,3 Fortunately for the healthy homologous donor, vasovagal reactions appear to be of minimal or no consequence. Whether the patient with coronary artery atherosclerosis is as resilient is unknown. Our use of saline to mute the effects of an


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.