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February 9, 1990, Vol 263, No. 6 >
ARTICLE | February 9, 1990

End-Tidal Pco2 During Cardiopulmonary Resuscitation

Max Harry Weil, MD, PhD; Raul J. Gazmuri, MD; Fulvio Kette, MD; Joe Bisera, MSEE; Eric C. Rackow, MD
JAMA. 1990;263(6):814-815. doi:10.1001/jama.1990.03440060054029.
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To the Editor.—  The contribution by Sanders et al1 strongly supports a series of earlier studies by our group, both experimental and clinical, on the rationale and hemodynamic significance of the end-tidal carbon dioxide tension (PETCO2) during cardiac arrest.2-4 Sanders and colleagues also deserve recognition for having initially observed a close relationship between PETCO2 and coronary perfusion pressure, an observation that we subsequently confirmed.5,6The importance of the PETCO2 measurement may, however, have been understated by the authors if it is viewed primarily as a prognostic indicator. In our own experience, it is the continuous measurement of PETCO2 and the extent to which the PETCO2 is moderated by therapeutic interventions that provides unique opportunities for therapeutic decision making. Yes, in the final analysis, the failure to achieve viable PETCO2

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AAM 2010;304:1493-1495.
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BMJ 2010;341:c5893-c1494.
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