Paraquat-poisoned victims in guarded condition

Phil Gunby
JAMA. 1982;248(19):2426-2427. doi:10.1001/jama.1982.03330190012004.
Text Size: A A A
Published online


A Georgia plant nurseryman and a Florida landscaper, both of whom accidentally inhaled large amounts of paraquat (1, 1′-dimethyl-4,4′-bipyridylium) herbicide, continue to survive after becoming the first humans since 1977 to undergo single-lung transplants. The former patient has also undergone a second lung transplant.

Until this recent resumption, only 38 human single-lung transplant attempts had been reported. These were attempted between 1963 and 1977, and patient survival ranged from about an hour to ten months. However, all were undertaken before the availability of cyclosporin A, which is credited with reducing rejection episodes and perhaps with enhancing healing of tracheal anastomoses and limiting postoperative infections.

The first single-lung transplant to be performed since 1977, on Aug 28 of this year, was at Toronto General Hospital. On Sept 20, a second lung transplantation was done there to replace the patient's other damaged lung.

Then, on Sept 24, another single-lung transplant was performed—this


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.