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May 19, 1989, Vol 261, No. 19 >
ARTICLE | May 19, 1989

Plastic Surgery

Michael C. Stalnecker, MD
JAMA. 1989;261(19):2877-2879. doi:10.1001/jama.1989.03420190153054.
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The past year has seen a flurry of activity by plastic surgeons exploring the exciting applications of tissue-derived factors in wound healing and bone formation. Other studies show promising new uses for tissue expansion and are revealing the mysteries of fetal scar formation. An increased understanding of the pathogenesis and treatment of sternal wound infections has improved the recovery from this catastrophic occurrence, while refinements in head and neck reconstruction using free flaps offer a significant improvement to patients disfigured by congenital deformity, trauma, or tumor.

Tissue-derived growth factors are now available in greater quantities due to biosynthesis through recombinant DNA technology. Researchers are now able to study their effects on the most basic problem in plastic surgery, wound healing, and have obtained exciting and promising results. Mustoe et al1 have found that plateletderived growth factors promote wound healing in rats and partially restore wound healing in surface-irradiated animals

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

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AAM 2010;304:1493-1495.
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BMJ 2010;341:c5893-c1494.
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