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Based on definitions approved by the Council of State and Territorial Epidemiologists, an imported case of CRS is defined as CRS in a U.S. or non-U.S. citizen whose mother was outside the United States during her presumed exposure to rubella. If the timing of exposure to rubella cannot be determined, the mother must have been outside the United States throughout the 21 days before conception and the first 20 weeks of her pregnancy.