With depression and mania as the unifying nidus of extremely intensive and extensive multidisciplinary psychobiologic research and clinical effort, it is timely that Georgotas leads 54 authors in collecting and evaluating this activity and progress.
Five hundred of the 653 pages, which are presented in six parts, focus on etiology, clinical syndromes, and treatment. Twenty of the authors are from New York City and New York state, while seven are from the National Institute of Mental Health. An equal number come from the rest of the United States and from foreign countries. Forty-seven of the authors have MD degrees. Two hundred twenty-six pages, the largest section, are devoted to treatment. About half of this presents psychopharmacology and medication therapy. References are included after each of the 42 chapters, and a topic index of 4 1/2 pages concludes the book.
On the broad research side are genetic studies (the Amish study