0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Serum Creatinine and Renal Function in the Elderly

Paul J. Hering, MD; Robert E. Carlson, MD
JAMA. 1982;248(1):31. doi:10.1001/jama.1982.03330010015013.
Text Size: A A A
Published online

To the Editor.—  We enjoyed Dr Gifford's article entitled "Isolated Systolic Hypertension in the Elderly" (1982;247:781). We would like to comment, however, on his statement that "serum creatinine level estimates renal function." With the decline in lean body mass with age, daily endogenous creatinine production decreases. Therefore, creatinine clearance must fall to a greater extent in the elderly before the serum creatinine level increases. This has recently been emphasized by Ouslander1 in a review of drug therapy in the elderly. The serum creatinine level may fall within the normal range in an elderly patient who has notable impairment of his renal function.2 A useful nomogram to estimate creatinine clearance in relation to age has been devised3: creatinine clearance = [(140-age) × body weight, kg]/[72 × serum creatinine] (multiply by 0.85 for females).This estimation is especially important when prescribing any medication that is eliminated by the kidney.

Topics

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();