We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Medical News

JAMA. 1981;245(18):1799-1807. doi:10.1001/jama.1981.03310430003001.
Text Size: A A A
Published online


New studies confirm MAO inhibitors' efficacy in treating severe anxiety  Benzodiazepine derivatives may no longer be the treatment of choice for the most extreme and intractable anxiety. In fact, those most in need of calmative therapy—patients with severe chronic phobias and panic disorders—are least likely to respond to these drugs. Diazepam and its cousins, however, remain useful agents for treating more mundane anxieties.For the treatment of extreme angst, antidepressants are finding growing favor. A few years ago, the news broke that tricyclics often benefit profoundly anxious persons such as those with agoraphobia. Now, a large, controlled double-blind study nearing completion confirms the lesser-known finding that monoamine oxidase inhibitors (MAOIs)—which retard amine metabolism in the brain—probably provide even more efficacious and specific therapy for the anxieties that besiege these patients.The MAOIs still are used principally by specialists with considerable expertise in psychopharmacology because of their severe potential toxicity.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...