This volume is presented as a reference for those interested in the laboratory diagnosis of hemoglobinopathies or in the clinical evaluation of hemoglobin genes. The publication is an outgrowth of laboratory manuals and a syllabus used in the Mayo Clinic laboratories and is supplemented with material from a workshop on hemoglobins and thalassemias, with contributions from experts at a number of institutions. Because the format is derived from long experience in explaining hemoglobin genes to laboratory personnel and physicians, the book is concise, clear, and meant to be useful.
The editor, Dr Virgil Fairbanks, is to be commended for constraining the experts to relatively brief, lucid state-of-the-art articles that introduce the subjects of hemoglobin variants, thalassemias, and their laboratory diagnosis. The second part of the book is devoted to "how-to" articles on the hemoglobin and thalassemia studies that should be used by any clinical laboratory that hopes to be definitive