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Surgical Treatment of Metastatic Cancer

James T. Ettien, MD
JAMA. 1988;259(24):3627-3628. doi:10.1001/jama.1988.03720240079048.
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As more and more patients are successfully treated for primary malignancy, surgeons are more and more confronted with the challenge of metastatic and recurrent malignancy. With the controversy surrounding the role of surgery in metastatic cancer, any text that organizes and clarifies the subject is welcome.

This text is edited by Steven Rosenberg, MD, PhD, chief of surgery at the National Cancer Institute. There are nine contributors, the majority from the National Institutes of Health.

The first of seven chapters is a tightly written overview of the biologic behavior of cancer that leads to metastases. This is necessarily written at the cellular and molecular level and brings to the reader the current state of knowledge in coherent form.

The next four chapters detail the two discrete organs most commonly encountered in metastatic disease: the lungs and the liver. The tight organization of the text is continued here—a chapter on the


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