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Torulopsis glabrata Endocarditis

H. Douglas Holliday, MD; Vincent Keipper, MD; Allen B. Kaiser, MD
JAMA. 1980;244(18):2088-2089. doi:10.1001/jama.1980.03310180054037.
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TORULOPSIS glabrata is a fungal organism of the family Cryptococcaceae with low pathogenicity for man. It is a frequent saprophyte and can be cultured from the stool, skin, mouth, and vagina in healthy persons. Infections due to T glabrata occur principally in patients whose immune systems are suppressed, have indwelling venous or urinary catheters, or have been treated with broad-spectrum antibiotics.1 Documented cases of endocarditis due to T glabrata are uncommon; predisposing causes and clinical features have not been reviewed.

A patient had tricuspid valve endocarditis secondary to T glabrata. Her illness followed abdominal surgery and was characterized by 33 months of episodic chills and fever. Other patients with T glabrata endocarditis have been described with features remarkably similar to those of our patient.2,3 These similarities prompted this case report and review of the literature.

Report of a Case  A 63-year-old diabetic woman had undergone a uretero-ureterostomy for


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