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Article |

Increased Renal Perfusion and Kidney Size in Convalescent Burn Patients

Cleon W. Goodwin, MD; Louis H. Aulick, PhD; Richard A. Becker, MD; Douglas W. Wilmore, MD
JAMA. 1980;244(14):1588-1590. doi:10.1001/jama.1980.03310140046029.
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Renal blood flow was elevated in convalescent burn patients shortly before discharge (992±112 mL/min/sq m in burn patients vs 551±37 mL/min/sq m in normal subjects; mean±SE). Autopsy studies demonstrated that renal enlargement was a constant feature of patients after a prolonged hospital course; the kidneys of 28 patients who died after 60 days of hospitalization weighed 241±10 g vs 153±8 g in control subjects. The increase in renal weight was primarily related to cellular hypertrophy and hyperplasia. These physiological and morphological findings in thermally injured patients may be a form of renal work hypertrophy following increased protein catabolism accompanying severe injury.

(JAMA 244:1588-1590, 1980)


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