Thyroid Dysfunction in the Ailing, Aging, and Aberrant

Laurence A. Gavin, MD
JAMA. 1980;243(13):1327. doi:10.1001/jama.1980.03300390013011.
Text Size: A A A
Published online

To the Editor.—  In the editorial on thyroid dysfunction, Nusynowitz and Young (242:275, 1979) speculated on the possible usefulness of serum reverse triiodothyronine (T3) levels in differentiating sick patients with isolated hyperthyroxinemia (low or normal serum T3 values) from sick patients with hyperthyroidism. We measured serum reverse T3 concentrations in the group of sick patients described in the same issue of The Journal (242:251, 1979).1 The mean serum reverse T3 concentration was significantly higher in the study group, at 65±20 ng/dL, vs 24±5 ng/dL (P<.05) in normal control subjects. Segregation of the sick patients into the "euthyroid sick" and "hyperthyroid sick" groups, however, revealed no significant difference in the reverse T3 means (61±20 ng/dL and 43±7 ng/dL, respectively). Thus, serum reverse T3 values seem to be of no value in distinguishing sick euthyroid patients with high serum free thyroxine indices from sick hyperthyroid patients.


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.