Reye Syndrome Surveillance—United States, 1986

JAMA. 1987;258(19):2645-2648. doi:10.1001/jama.1987.03400190027008.
Text Size: A A A
Published online


CDC.  Influenza—United States, 1985-1986 season . MMWR 1986;35:470,475-9.
CDC.  Summary of notifiable diseases, United States, 1986 . MMWR 1987 (in press).
Hurwitz ES, Barrett MJ, Bregman D, et al.  Public Health Service study on Reye's syndrome and medications: report of the pilot phase . N Engl J Med 1985;313:849-57.
Link to Article[[XSLOpenURL/10.1056/NEJM198510033131403]]
Hurwitz ES, Barrett MJ, Bregman D, et al.  Public Health Service study of Reye's syndrome and medications: report of the main study . JAMA 1987;257:1905-11.
Link to Article[[XSLOpenURL/10.1001/jama.1987.03390140075030]]
Remington PL, Rowley D, McGee H, Hall WN, Monto AS.  Decreasing trends in Reye syndrome and aspirin use in Michigan, 1979 to 1984 . Pediatrics 1986;77:93-8.
Barrett MJ, Hurwitz ES, Schonberger LB, Rogers MF.  Changing epidemiology of Reye syndrome in the United States . Pediatrics 1986;77:598-602.
The CDC case definition is (1) acute noninflammatory encephalopathy documented by alteration in the level of consciousness and, if available, a record of cerebrospinal fluid containing eight leukocytes or less per mm3, or histologic sections of the brain demonstrating cerebral edema without perivascular or meningeal inflammation; (2) hepatopathy documented by either biopsy or autopsy considered to be diagnostic of RS or by a threefold or greater rise in the levels of either serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic-pyruvic transaminase (SGPT), or serum ammonia; and (3) no more reasonable explanation for the cerebral or hepatic abnormalities.


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.