0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Massive Overdose and Death From Prophylactic Lidocaine

Bruce Burlington, MD; Curt R. Freed, MD
JAMA. 1980;243(10):1036-1037. doi:10.1001/jama.1980.03300360012010.
Text Size: A A A
Published online

To the Editor.—  Lidocaine hydrochloride has been recommended as an antiarrhythmic agent for patients with acute myocardial infarction even before they show development of arrhythmias.1 There have been several studies attempting to show the value of prophylactic lidocaine.2 While the routine administration of lidocaine will reduce the incidence of ventricular tachycardia and fibrillation, these arrhythmias can be treated as they appear, and no study has shown that prophylactic lidocaine leads to a significant reduction in mortality.3 Furthermore, major toxic reactions, including seizures, arrhythmias, and myocardial depression, are associated with lidocaine use.We report a case of fatal lidocaine toxic reaction caused by accidental administration of a bolus overdose that had been intended as a prophylactic loading dose.

Report of a Case.—  A man in his 60s with a history of angina and previous myocardial infarction came to the emergency room complaining of left infrascapular chest pain of

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();