0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Fatal Anaphylactoid Reaction After Dextran 40 Administration

Edith Flatau, MD; Peretz Resnitzky, MD
JAMA. 1980;243(10):1035-1036. doi:10.1001/jama.1980.03300360011006.
Text Size: A A A
Published online

To the Editor.—  In the letter "Severe Anaphylaxis in Cirrhotic Patients Receiving Dextran 40," Adar and Schneiderman (237:119, 1977) suggested an increased sensitivity to dextran in cirrhotic patients. We report a case of fatal anaphylactoid reaction to dextran 40.

Report of a Case.—  A 52-year-old man, who was a heavy smoker and alcohol drinker, was suffering from chronic obstructive lung disease and thrombotic occlusion of the abdominal aorta. He was hospitalized because of a superimposed infection to his chronic obstructive lung disease, which caused a severe deterioration in his general condition. On admission he was cyanotic, confused, and dyspneic. Signs of occlusion of the abdominal aorta, with paraparesis attributed to the secondary involvement of the anterior spinal artery, were found. Liver function test results were greatly impaired: SGOT, 800 units/mL; SGPT, 1,025 units/mL; bilirubin, 3 mg/dL. The pH was 7.27; the pO2 was 40 mm Hg; and the pCO

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();