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ARTICLE |

Neuropsychiatric Side-Effects of Drugs In Elderly

Joseph A. Flaherty, MD
JAMA. 1979;242(19):2118. doi:10.1001/jama.1979.03300190054033.
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ABSTRACT

This volume provides essentially what it promises—a comprehensive overview of neuropsychiatric complications of medical drugs in the elderly. It is readable and useful, providing a sound compromise between a highly academic orientation and a mere catalogue of drug reactions. When necessary, the biochemical, physiological, and pharmacokinetic bases of drug reactions are reviewed; this is a useful tack, as some practitioners may have forgotten these facts and have difficulty with the volume otherwise.

Most chapters cover the general side effects of the drug categories rather than just those specifically related to the elderly population. For example, the chapter on antihypertensives discusses the symptoms of side effects such as impotence, fatigue, depression, hypokalemia, hyponatremia, delirium, and hallucinosis in the general population. These inclusions enhance the volume's applicability. The authors have also provided estimates or data as to the relative frequency of different side effects as well as the management of them. Chapters

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