September 7, 1979, Vol 242, No. 10 >

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ARTICLE | September 7, 1979

The Increasing Importance of Polymicrobial Bacteremia

Daria Kiani, MD; Edward L. Quinn, MD; Keith H. Burch, MD; Tom Madhavan, MD; Louis D. Saravolatz, MD; Thomas R. Neblett, PhD

JAMA. 1979;242(10):1044-1047. doi:10.1001/jama.1979.03300100022015.

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Polymicrobial bacteremia increased from 6% in 1970 to 13% in 1975 in patients with bloodstream infections. This type of serious infection most commonly complicated genitourinary (27%) and gastrointestinal (26%) conditions, frequently followed invasive procedures (68%), was more common in hospitalized patients (73%), and was often associated with malignancies (25%) or immunosuppressive or cancer chemotherapy (34%). Although polymicrobial endocarditis was more commonly encountered in recent years, this infection accounted for only 4.5% of patients with multiple organism bacteremias. Gram-negative aerobic bacteria were isolated from 62% and anaerobic bacteria in 39% of patients with polymicrobial bacteremia compared with 37% and 14%, respectively, in patients with monomicrobial bacteremia. In the 88 patients with polymicrobial bacteremia, the mortality was 44.5%, compared with 18.0% in patients with monomicrobial bacteremia.

(JAMA 242:1044-1047, 1979)

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Kiani D, Quinn EL, Burch KH, Madhavan T, Saravolatz LD, Neblett TR. The Increasing Importance of Polymicrobial Bacteremia. JAMA. 1979;242(10):1044-1047. doi:10.1001/jama.1979.03300100022015.

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