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August 17, 1979, Vol 242, No. 7 >
ARTICLE | August 17, 1979

Blood Resource Management

John Bernard Henry, MD; Robert C. Hubbell, MSP
JAMA. 1979;242(7):621-622. doi:10.1001/jama.1979.03300070017016.
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THE RISK of posttransfusion hepatitis associated with blood from compensated donors is estimated to be from three to ten times greater than that from blood given by volunteer donors. Anywhere from 10,000 to 30,000 cases of overt hepatitis occur each year as a result of blood transfusion. Further, there may be as many as 100,000 subclinical cases that go unreported. Citing the lifethreatening hazard that accompanies the use of blood from paid donors, the Food and Drug Administration in 1978 published a regulation requiring that blood be distinguished by source. Prominently marked labels bearing the statement "volunteer donor" or "paid donor" now must appear on each container of whole blood or components intended for transfusion.

At the same time, limits on the capability of detecting viral hepatitis in donor blood suggest that the disease will continue to be transmitted through transfusion. Thus, while hepatitis remains a problem of no small

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