Use of Prophylaxis for Malaria by American Travelers to Africa and Haiti

Hans O. Lobel, MD; Carlos C. Campbell, MD; Marguerite Pappaioanou, DVM, PhD; Alan Y. Huong, PhD
JAMA. 1987;257(19):2626-2627. doi:10.1001/jama.1987.03390190104029.
Text Size: A A A
Published online

EACH year, approximately 1 million Americans travel to countries where they may be exposed to malaria.1 Infections with Plasmodium falciparum in such travelers are of particular concern because these infections can be fatal.2 Use of effective chemoprophylaxis can reduce the risk of infection from malaria considerably.3 All travelers to malariaendemic countries are advised to take chloroquine each week as chemoprophylaxis. In addition, from 1982 until April 1985, the Centers for Disease Control (CDC) advised travelers to countries with chloroquine-resistant P falciparum to also take pyrimethamine-sulfadoxine each week.4 However, information on cases of malaria in the United States reported to the CDC suggests that use of chemoprophylaxis by US travelers is incomplete: only 28% of the 410 US patients infected with P falciparum in Africa between 1980 and 1984 had used a recommended drug regimen for prophylaxis, and none of the 58 patients with P falciparum infections


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.