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Surveillance of Nosocomial Infections by Antibiotic Monitoring

Lynn Feldman; Margaret Lamson, RN, MPH; Joseph F. Gallelli, PhD; John E. Bennett, MD
JAMA. 1979;241(26):2806-2807. doi:10.1001/jama.1979.03290520030020.
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Records of all patients receiving intravenous gentamicin sulfate during a 92-day interval were reviewed to detect nosocomial infections that had been missed by routine surveillance. Only 46 of 48 of the 99 treatment courses had been detected. In 96% of cases not detected by routine surveillance, use of gentamicin was considered justified. Of the patients missed by surveillance, 83% were in oncology wards, and 46% had severe neutropenia and fever of unknown origin. Antibiotic surveillance proved a useful adjunct in estimating the incidence of nosocomial infections in such patients.

(JAMA 241:2806-2807, 1979)

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