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June 15, 1979, Vol 241, No. 24 >
ARTICLE | June 15, 1979

Medical News

JAMA. 1979;241(24):2585-2596. doi:10.1001/jama.1979.03290500003001.
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ABSTRACT

Deep hypothermia for infant open heart surgery: pros and cons  Baby mammals, cooled to a state of profound hypothermia, can survive lengthy periods of circulatory arrest. Though the offspring of natural hibernators such as infant ground squirrels probably are the champions, human infants also can outlast their adult counterparts at temperatures too low to sustain circulation.Because of this capacity, an infant undergoing open heart surgery can be safely subjected to deep hypothermic circulatory arrest for an hour or longer. Hypothermia protects the tissues from ischemia during total circulatory arrest, and the arrest itself enables surgeons to operate in a bloodless field, unimpeded by the cannulas that make surgery on a tiny heart so tricky.Some practitioners, however, now believe that deep hypothermic arrest may damage the CNS. Hence, critics of the procedure are beginning to favor continuous perfusion with moderate hypothermia, even for the smallest patients.Continuous perfusion

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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