0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Bacterial Vaginosis and the Outcome of Pregnancy

Michael Feingold, MD; Anthony J. Sbarra, PhD
JAMA. 1987;257(11):1475. doi:10.1001/jama.1987.03390110051025.
Text Size: A A A
Published online

To the Editor.—  Gravett and associates1 are to be congratulated for their work on the association of bacterial vaginosis and premature rupture of the membranes. They suggest that the mechanism by which maternal cervical or vaginal infection may cause preterm labor or preterm premature rupture of the membranes may involve bacterial phospholipase A2 and subsequent cleaving of bound arachidonic acid from the phospholipid components of fetal membranes. The resulting free arachidonic acid, an obligate precursor of prostaglandin, would now be available for prostaglandin synthesis and the initiation of labor and preterm premature rupture of the membranes. Some recent work in our laboratory supports this concept.

Study.—  We have developed an in vitro experimental model that has allowed us to study amniotic lysosomal enzyme release (ie, phospholipase A2) under controlled conditions.2 A layer of human amniotic membranes was mounted on a specially designed reaction vessel serving as

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();