Eleven years ago, I had the opportunity to review the second edition of Cancer Medicine by Holland and Frei in JAMA. This year the third edition of this text has been published, and I am once again afforded the privilege of reviewing it. In the preface the authors state that the third edition is an entirely new book. The number of editors has been expanded from two to six, which includes Dr Donald L. Morton (surgical oncology) and Dr Ralph R. Weichselbaum (radiation oncology). Two hundred ninety-nine experts, many of whom are new, have contributed.
The first 1080 pages are devoted to basic principles of cancer biology, tumor immunology, cancer etiology and epidemiology, clinical trials, prevention, screening and early detection, cancer pathology, principles of imaging, interventional radiology, endoscopy, principles of surgical oncology, radiation oncology, medical oncology, chemotherapy, chemotherapeutic agents, endocrine therapy, biologics and biotherapeutics, bone marrow transplantation, psychooncology, oncology nursing,