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Stroke: Pathophysiology, Diagnosis, and Management

Jonathan H. Pincus, MD
JAMA. 1987;257(7):984. doi:10.1001/jama.1987.03390070104036.
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This is a superb, encyclopedic work on stroke. The book represents a fine balance between epidemiology and pathophysiology and a thorough, comprehensive review of clinical aspects of stroke, both hemorrhagic and occlusive. Particularly effective are the studies by Powers and Raichle on positron emission tomography in cerebral vascular disease and by Buonanno on magnetic resonance imaging in stroke. These discussions contain a great deal of pathophysiological data as well as important practical clinical information. Beautifully illustrated studies on computed tomography and cerebral angiography follow, along with clear and balanced studies on noninvasive tests for carotid disease. The topics of surgery, anticoagulation, and antiplatelet agents are fully addressed and are the best treatment of this subject that this reviewer has encountered.

One article that epitomizes the thoroughness and completeness of this book is the chapter by Tatemichi and Moore on migraine and stroke, a subject that has not been treated with


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