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Intrathoracic Tuberculous Lymphadenopathy in Adults

Sandeep Dhand, MD; Mary Fisher, MD; J. William Fewell, MD
JAMA. 1979;241(5):505-507. doi:10.1001/jama.1979.03290310045018.
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THE INCIDENCE of pulmonary tuberculosis in the United States has decreased so dramatically over the last few decades1 that the disease is frequently unrecognized on admission to general as well as to urban teaching hospitals.2,3 The change in the clinical and roentgenographic spectrum of pulmonary tuberculosis in the adult has recently been emphasized by Khan et al.4 Mediastinal or hilar lymphadenopathy secondary to tuberculosis, though common in children with primary tuberculosis,5,6 has been reported as an unusual mode of presentation of tuberculosis in the adult.4,7,8 This type of nodal enlargement usually suggests the presence of a malignant process or sarcoidosis, and tuberculosis is often not considered in the differential diagnosis.9,10

This study is a retrospective analysis of 33 cases of adult tuberculosis with intrathoracic lymphadenopathy detected during the last 20 years at this institution and at the Philadelphia General Hospital. The purpose of this

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