Cardiopulmonary Resuscitation

To the Editor.—  In the "Standards and Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiac Care (ECC),"¹ the following errors were noted. On page 2941, the authors state that one ampule (400 mg) of dopamine hydrochloride, when mixed in 250 mL, produces a concentration of 800 μg/mL. Actually, the above formulation produces a concentration of 1600 μg/mL. The authors go on to say that 2-mg vials of nitroglycerin, when diluted in 250 mL, result in a concentration of 80 μg/mL. This would actually yield a concentration of 8 μg/mL. Finally, the authors give the initial dose of sodium nitroprusside as 10 to 20 mg/min. Such a regimen would cause a 70-kg patient to receive 20 to 30 times the maximum recommended dose, according to current product prescribing information (dosage range, 0.5 to 10 μg/kg/min).While such inadvertent manuscript errors might be considered trivial in the general medical literature, they