David B. Redwine, MD
JAMA. 1986;256(10):1296. doi:10.1001/jama.1986.03380100070020.
Text Size: A A A
Published online

To the Editor.—  I would appreciate it if Cramer et al1 could clarify some points regarding the methodology and conclusions of their case-control study on endometriosis. The first question concerns their use of infertility as the main symptom to select cases, since pain may actually be a more common symptom.2 Second, since cases were older than controls and since ovulatory function declines with age, it seems the study apparently did not control for possible decline in ovulation (their menstrual cycle data notwithstanding). The infertility observed might therefore in some large part be age related, not endometriosis related.Third, some of the controls may have had endometriosis, and if these were to be eliminated, this would change some of the observed risk ratios, particularly relating to their observations on height and smoking before the age of 17 years, differences that seemed less firm to begin with. Fourth, their findings


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.