We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Smallpox Eradication A Global Appraisal

Paul F. Wehrle, MD
JAMA. 1978;240(18):1977-1979. doi:10.1001/jama.1978.03290180051024.
Text Size: A A A
Published online


OF ALL communicable diseases limited to man, few have the attainable prospect of complete and permanent eradication. Of those few, smallpox has provoked the greatest interest. In 1801, Jenner1 entertained the prospect of eradication soon after demonstrating the efficacy of vaccination in protecting the susceptible individual. Despite the early and continuing interest in this possibility and the control or even successful eradication in some individual countries, the first systematic international program was proposed in 1949 by Soper,2 then director of the Pan American Sanitary Bureau. Failure of the individual country efforts and increasing incidence of disease in the Americas facilitated the adoption and implementation of a resolution to approve such a program. Budgetary provision was made in 1950 by the 13th Pan American Sanitary Conference.3,4

The lessons learned in this and in the subsequent global program are important in understanding the success in the imminent total global eradication


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.