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Mycobacterium tuberculosis Bacteremia in the Acquired Immunodeficiency Syndrome

Brian R. Saltzman, MD; Mary R. Motyl, PhD; Gerald H. Friedland, MD; John C. McKitrick, PhD; Robert S. Klein, MD
JAMA. 1986;256(3):390-391. doi:10.1001/jama.1986.03380030092036.
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THE ACQUIRED immunodeficiency syndrome (AIDS) is characterized by a defect in cellular immunity and the occurrence of opportunistic infections or unusual malignant neoplasms. The most commonly reported bacterial infection suggestive of a defect in cellular immunity, which meets the Centers for Disease Control (Atlanta) case definition for AIDS, is disseminated Mycobacterium avium-intracellulare infection.1 Disseminated infection due to Mycobacterium tuberculosis has also been reported in AIDS.2 Bacteremia is common in disseminated M avium-intracellulare infection in patients with AIDS.3 In contrast, bacteremia in disseminated M tuberculosis is rare4-6 and has not been reported previously in patients with AIDS, to our knowledge. We recently diagnosed disseminated infection due to M tuberculosis, in which bacteremia also occurred, in an intravenous drug abuser with AIDS.

Report of a Case  A 35-year-old man with a three- to five-year history of intravenous heroin and cocaine abuse developed anorexia and weight loss in November


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