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Osteopenia and Bone Fractures in a Man With Anorexia Nervosa and Hypogonadism

Nancy A. Rigotti, MD; Robert M. Neer, MD; Larry Jameson, MD, PhD
JAMA. 1986;256(3):385-388. doi:10.1001/jama.1986.03380030087034.
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Women with anorexia nervosa have reduced skeletal mass. Both anorexia and osteopenia are less common in men. We describe a 22-year-old man with anorexia nervosa and severe osteopenia involving both cortical and trabecular bone who developed a pelvic fracture and multiple vertebral compression fractures. He was found to have secondary hypogonadotropic hypogonadism that was reversible with weight gain. This case illustrates the need to consider osteopenia as a potential complication of anorexia nervosa in males as well as females.

(JAMA 1986;256:385-388)


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