Medical News

JAMA. 1978;240(4):333-341. doi:10.1001/jama.1978.03290040011002.
Text Size: A A A
Published online


Blood studies soon may show who is at risk for rheumatoid arthritis  The results of a new study showing that nearly three fourths of patients with rheumatoid arthritis (RA) have one or more of three particular histocompatibility antigens as well as a common B lymphocyte marker have added to the growing belief that susceptibility to this most serious form of arthritis is genetically controlled.The study, performed by Allan Gibofsky, MD, research associate at Rockefeller University in New York, and colleagues, shows that in blood tests on 53 patients, a highly specific group of human typing sera reacted positively with lymphocytes of 70% of patients with RA, as opposed to only 20% of normal persons.According to Dr Gibofsky, the ability to identify patients predisposed to RA might result in earlier and better treatment and could be important to researchers trying to learn what factors trigger the disease. The


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.