We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Diabetic Ketoacidosis Appearing as Carbon Monoxide Poisoning

John E. Hodgkin, MD; David M. Chan, ARRT
JAMA. 1975;231(11):1164-1165. doi:10.1001/jama.1975.03240230038018.
Text Size: A A A
Published online


THE VALUE of the differential spectrophotometer in determining hemoglobin values and saturations of carboxyhemoglobin (COHb) and oxyhemoglobin (O2Hb) has been demonstrated.1 The differential spectrophotometer (IL 182 CO-Oximeter) is used in our pulmonary function laboratory for routine blood-gas analysis.

Recently, a comatose patient was first seen in the emergency room with metabolic acidosis. Carbon monoxide poisoning was suspected on the basis of initial arterial blood-gas testing, which showed a markedly increased level of COHb. However, it was subsequently determined that the patient had very high levels of serum lipids resulting in interference with the analyzer's spectrophotometric method for measuring hemoglobin, COHb, and O2Hb.

Since this problem with the differential spectrophotometer we use has not previously been described, we decided to collect some quantitative data on the effect of serum lipids on the performance of this machine.

Report of a Case  The patient was a 27-year-old woman


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.