0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

One-Stage Replantation of Both Lungs in the Dog

Fikri Alican, MD; Mukadder Cayirli, MD; Erol Isin, MD; James D. Hardy, MD
JAMA. 1971;215(8):1301-1306. doi:10.1001/jama.1971.03180210047009.
Text Size: A A A
Published online

In clinical lung allotransplantation, the recipient's remaining diseased lung has caused severe ventilation perfusion imbalance in the graft. We have performed one-stage bilateral lung replantation on 26 dogs as a prototype for possible future solution of this physiologic problem. Pulmonary edema was the main cause of death. Ten dogs lived more than 1 month after operation; seven are still alive and vigorous up to 6 1/2 months. X-ray films of the chest, pulmonary arterial pressures, angiograms, and blood gas levels are normal. Conclusions are that (1) pulmonary edema is proportional in severity to the degree of anoxic damage to the graft, and is potentially reversible; (2) one-stage total pulmonary denervation is readily tolerated by the dog; and (3) simultaneous bilateral lung replantation with long-term survival and nearly normal dynamics of ventilation and pulmonary circulation is feasible.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();