Cardiac tumor emboli to the brain are rare. Previously reported cases have all been associated with myxoma of the left atrium, and, to our knowledge, an embolus associated with a myxoma of the ventricle has not been previously reported. The patient had two episodes of recurrent hemiplegia following periods of excessive exertion. Carotid angiography demonstrated a complete occlusion of the left middle cerebral artery. Echocardiography also proved valuable in diagnosis. Microscopic examination of this vessel revealed the lesion to be a myxoma which had originated from a myxoma of the apex of the left ventricle. This etiologic factor should be considered in the occurrence of cerebrovascular occlusive disease in the young adult.