Recent years have seen a proliferation of textbooks and mini-textbooks exhibiting a wide variation of quality. This volume stands out in many ways: it addresses itself specifically to known and postulated pathophysiologic mechanisms without being overburdened with details that would interest only the superspecialist; it is concisely and clearly written, and clearly succeeds in its avowed purpose of providing the answers regarding the why and how of neurologic disease; and it is refreshingly free of the cookbook type of approach. Most important, however, it vigorously imparts the excitement and intellectual stimulation to be derived from applying the basic neurological sciences to clinical problems.
In a book that is surprisingly comprehensive, it was disappointing not to find any discussion of the pathophysiology of the effects of two common and important diseases on the nervous system, alcoholism and diabetes.
The single major criticism relates to the statements about the cerebrospinal fluid (CSF)