Application of Diethyl Ether to Herpes Simplex Lesions

H. D. Mintun Jr, MD
JAMA. 1978;239(9):831. doi:10.1001/jama.1978.03280360027006.
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To the Editor.—  For many years, I have used an excellent, practical, safe solution to the problem of the application of diethyl ether to herpes simplex lesions (238:1631, 1977) and have had no complaints from patients concerning the safety of the following method.I advise them to purchase an aerosol container of engine-starting fluid and warn them as to the directions on the container about its explosive nature. Inasmuch as this product has been used by millions of people over the years, including myself for other purposes, the safety rules concerning its use are well documented.The instructions to the patient concerning application to the herpes lesions involves early detection of the recurrence by means of the pain that exists. This always precedes the emergence of the lesions. At this time, the patient takes a cotton-tipped applicator, places it at the orifice in the head of the aerosol can, releases


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