0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Immunity and Oncogenesis

Zenonas Danilevicius, MD
JAMA. 1974;230(8):1179. doi:10.1001/jama.1974.03240080061037.
Text Size: A A A
Published online

Approximately at the time when Osoba and Miller1 described the thymic factor and indicated that through this factor thymus endows the lymphoid cells with power to participate in the phenomenon of immunity, Perri et al2 spoke about thymus as follows:

The thymus and its function could be of particular importance in the field of oncology since it might participate, along with other glands, in the regulation of tissue homeostasis and be of paramount importance in regressing the activity of cells which potentially may develop into neoplasms.

Perri et al found that Jensen sarcoma grew at a faster rate in thymectomized animals than in normal controls. Since that time, other authors have indicated that in animals and in humans who have been immunosuppressed, the incidence of malignant tumors was higher than in those with normal immunity status.

In 1972, Penn and Starzl3 demonstrated that human organ transplant recipients

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();