Multiple Myeloma in a Young Person

ROMESH Kohli, MD; Adrian Vladutiu, MD
JAMA. 1978;239(4):295-296. doi:10.1001/jama.1978.03280310027011.
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To the Editor. —  Cases of multiple myeloma in young people are very rare.1-3 In some of the cases reported, there were no hallmarks of myelomas, and, in fact, there were more benign plasmacytic tumors.3 We present a case of a man who showed all the characteristic features of multiple myeloma and had a short clinical course.

Report of a Case.—  A 25-year-old man was admitted to the hospital for management of chronic renal failure. Four months previously he had complained of increasing weakness, back pain, and weight loss. One month prior to this hospitalization he was admitted to another hospital where hemodialysis was begun. At his last admission he had bradycardia (55 beats per minute), paralysis of the left side of the face, generalized peripheral lymphadenopathy, a palpable tip of the spleen, and a slightly enlarged liver. The hemoglobin level was 5.6 g/dl, and the ESR was


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