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ARTICLE |

Antihypertensive Drugs And Stroke

S.K. Robinson, MD
JAMA. 1974;230(3):374-375. doi:10.1001/jama.1974.03240030016012.
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ABSTRACT

To the Editor.—  The cooperative study, "Effect of Antihypertensive Treatment on Stroke Recurrence" (229:409, 1974) is a milestone since it shows that a fall in blood pressure is not followed by benefits in most patients. It shows also what has long been suspected, that mild hypertension may not be benefited by drug treatment. White men and blacks of both sexes obtained neither cerebral nor cardiovascular benefit; some subgroups (mild hypertensives or elderly black men) may have been at a disadvantage while taking drugs.There were six cases of congestive heart failure in those subjects given placebos, and none in those given drugs. Five failures were among the 35 white women. There was only one instance in four years among the 417 blacks and white men. The authors thought the improvement in congestive heart failure to be the chief benefit from drug use. However, significant cardiovascular benefits from drugs were not

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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