Antiviral Drugs

William R. Barclay, MD
JAMA. 1977;238(23):2531-2532. doi:10.1001/jama.1977.03280240077032.
Text Size: A A A
Published online

A few among us may recall the excitement and astonishment that we experienced when first having access to penicillin to treat serious or life-threatening infections. With the discovery of this antibiotic, a new class of therapeutic agents was founded, and there opened before us therapeutic vistas beyond anything we had dreamed of. The second major antibiotic to be introduced was streptomycin for the treatment of tuberculosis. For the first time, we witnessed recoveries from tuberculous meningitis, a disease that had resulted in 100% mortality. The privilege of using these miracle drugs shortly after their discovery was, for some of us, the most exciting experience of our lifetime. In the years that have followed, we grew accustomed to the discovery of powerful new therapeutic agents, accepted their introduction into medicine with little or no fanfare, and lost the excitement and admiration they should have invoked in us.

However, the development of


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.