0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Treatment of Acute Cold Agglutinin Hemolytic Anemia With Transfusion of Adult i RBCs

Judith E. Woll, MD; Charles M. Smith, MD; Jacob Nusbacher, MD
JAMA. 1974;229(13):1779-1780. doi:10.1001/jama.1974.03230510053024.
Text Size: A A A
Published online

ACUTE cold agglutinin disease with severe hemolysis following primary atypical pneumonia was first described in 1943 by Horstmann and Tatlock.1 In a 1945 review of 200 cases of primary atypical pneumonia, 11 had hemolytic anemia of varying severity, which resulted in two deaths.2 Despite subsequent identification of the specificity of the cold autoantibody (anti-I), transfusion of such patients has been limited by the difficulty in obtaining compatible blood.

We report a patient with severe hemolysis associated with acute postinfectious cold agglutinin disease who was treated with transfusions of the rare, type i red blood cells (RBCs).

Report of a Case  A 51-year-old nulliparous white woman was admitted in October 1972 with a twoweek history of fever and cough, productive of yellow sputum, for which she took prescribed tetracycline for ten days. The fever remitted, but the cough persisted. Two days before admission, nausea and vomiting developed, and the

Topics

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

93 Views
0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
×
brightcove.createExperiences();