This book emanates from a neurosurgical center with considerable experience in the chemotherapeutic management of malignant brain tumors. The dust jacket advertises the book as not only presenting the concepts underscoring the strategy of chemotherapy for primary malignant tumors of brain, but also as reviewing the extensive clinical experience at the University of California School of Medicine, San Francisco. The book delivers on the first item but unfortunately not on the second.
There is no question that the management of malignant brain tumors is an exceptionally urgent clinical problem and one that merits a comprehensive review. Anyone nurturing an interest in the clinical application of a chemotherapeutic program for malignant gliomas will benefit from the superb reviews of cell kinetics, pharmacodynamics, and experimental brain tumor models. These chapters are current outlines of the state of the art and have many valuable references. The very trenchant foreword submitted by Dr Boldrey